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J Radiat Prot Res > Volume 40(3);2015 > Article
Journal of Radiation Protection and Research 2015;40(3):168. doi: https://doi.org/10.14407/jrp.2015.40.3.168
방사선 조사된 국내 야생 등줄쥐 (Apodemus agrarius coreae) 장기무게 및 비장세포 세포고사
주현진;최훈;양광희;금동권;김희선;
Organ Weights and Splenocytic Apoptosis in γ-irradiated Korean Dark-Striped Field Mice, Apodemus Agrarius Coreae
Joo, Hyunjin;Choi, Hoon;Yang, Kwang-hee;Keum, Dong-kwon;Kim, Hee sun;
ABSTRACT
The present investigation was planned to estimate potential possibility of striped field mice, Apodemus agrarius coreae (A. a. coreae), as a biological dosimeter in radio-environmental ecology. We bred captured wild A. a. coreae at laboratory and classified taxonomically based on external, cranial and tooth characters. Organ weights and splenocytic apoptosis were observed in order to establish a basic data on radiation biology of A. a. coreae (male, 40 weeks old). The biological effects was observed at 24hrs following irradiation (doses : 0, 0.5, 1, 2 Gy, dose rate : $0.8Gymin^{-1}$, $^{137}Cs$). Only thymus weights was significantly decreased. Splenocytic apoptosis was increased after irradiation. But splenocytic apoptosis was decreased in 0.5 Gy ${gamma}$-irradiated mice compared to those of 0, 1, 2 Gy (P < 0.05). These data suggested that events in thymus and spleen of Korean dark-striped field mice, A. a. coreae THOMAS, could be a potential radio-biological indicator in human environments.
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