To know radon and uranium concentration variations in groundwater with regional difference, groundwaters were sampled at five different Daejeon area. Seventy-five samples were analyzed and forty samples were collected twice at drying and after raining season to know surface water effect. The average radon and uranium concentration of five areas are $270.9{pm}152.3;Bq/L,;43.8{pm}23.5;{mu}g/L$ at Yusung-gu, $112.9{pm}65.8;Bq/L,;0.45{pm}0.23;{mu}g/L$ at Seo-gu, $41.3{pm}24.0;Bq/L,;4.9{pm}11.3;{mu}g/L$ at Dong-gu, $131.8{pm}99.5;Bq/L,;54.3{pm}127.5;{mu}g/L$ at Daeduk-gu and $44.0{pm}43.0;Bq/L,;8.1{pm}11.6;{mu}g/L$ at Jung-gu. The mean concentrations of analyzed samples to know surface water effect were ranged from 0.5 to 640 ${mu}g/L$ for uranium and from 0.4 to 729 Bq/L for radon. The average concentration of radon and uranium after raining season were lower than those of drying season. The mean contents of radon End Uranium at drying season were $253{pm}14;Bq/L,;63{pm}12.2;{mu}g/L$, and $195{pm}11;Bq/L,;45.4{pm}11.7;{mu}g/L$ after raining season.