1Research Center, Dongnam Institute of Radiological & Medical Sciences, Busan, Republic of Korea 2Department of Biomedical Engineering, Inje University, Gimhae, Gyeongnam, Republic of Korea 3Department of Physics, Dong-A University, Busan, Republic of Korea
Received: July 29, 2015; Revised: November 4, 2015 Accepted: November 10, 2015.
ABSTRACT
The low dose radiation is done for a long period, thus researchers have to know the exact dose distribution for the irradiated mouse. This research has been conducted in order to find out methods in transmitting an exact dose to mouse in a mouse irradiation experiment carried out using 137Cs irradiation equipment installed in the DIRAMS (Dongnam Institution of Radiological & Medical Sciences) research center. We developed a single mouse housing cage and shelf with adjustable geometric factors such as distance and angle from collimator. The measurement of irradiated dose showed a maximal 42% difference of absorbed dose from the desired dose in the conventional irradiation system, whereas only 6% difference of the absorbed dose was measured in the self-developed mouse apartment system. In addition, multi mice housing showed much difference of the absorbed dose in between head and body, compared to single mouse housing in the conventional irradiation system. This research may allow further research about biological effect assessment for the low dose irradiation using the self-developed mouse apartment to provide more exact doses which it tries to transmit, and to have more reliability for the biological analysis results.
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